Claisen condensation

克萊森酯縮合反應

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克萊森縮合反應（Claisen縮合反應）是指兩分子羧酸酯在強鹼（如乙醇鈉）催化下，失去一分子醇而縮合為一分子β-羰基羧酸酯的反應。參與反應的兩個酯分子不必相同，但 ...

Claisen condensation

https://en.wikipedia.org

The Claisen condensation is a carbon–carbon bond forming reaction that occurs between two esters or one ester and another carbonyl compound in the presence ...

Claisen Condensation

https://byjus.com

The Claisen condensation reaction is an organic coupling reaction that results in the formation of a C-C bond between either a single ester and one carbonyl ...

23.7

https://chem.libretexts.org

During the reaction a new carbon-carbon is formed to produce a β-keto ester product. This reaction is considered a condensation because it ...

Acetoacetic

https://www.organic-chemistry.

The Claisen Condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters. The driving force is the ...

Claisen Condensation and Dieckmann Condensation

https://www.masterorganicchemi

The Claisen condensation is a key reaction of esters. It's a nucleophilic acyl substitution between an enolate and an ester.

Claisen Condensation

https://www.sciencedirect.com

Claisen condensation first discovered by Rainer Ludwig Claisen in 1887 is a carbon-carbon coupling reaction between two esters or one ester and another carbonyl ...

Claisen Condensation Reaction Mechanism

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13.4

https://chem.libretexts.org

In a typical retro-Claisen reaction, a thiol (or other nucleophile such as water) attacks the carbonyl group of a β-thioester substrate (step 1) ...

Claisen Condensation

https://www.sciencedirect.com

The Claisen condensation – strictly the condensation of two esters with the concomitant release of one of the constituent alcohol moieties – is arguably the ...